Scotland made two changes to their final Six Nations match against France on Saturday in Paris.
Gregor Brown replaces Johnny Gray in the second row, and Matt Fergerson arrives behind injured Jack Dempsey.
Marshall Sykes and Ben Mancuster have their bench names and will play the first six countries.
France is in the box sheet to win the title in Paris after beating Ireland in Dublin last week.
England aims to take care of their business in Cardiff with Wales before hoping Scotland will cause upsets late in the evening.
Ireland begins an afternoon action against Italy in Rome.
The Scotland XV will be playing against France.
Pierre Schumann, Dave Cherry, Xander Fagerson, Gregor Brown, Grant Gilchrist, Jamie Richie, Rory Darge (co-captain), Matt Fergerson, Ben White, Finn Russell, Duhan van der Melwe, Tom Jordan, Who Jones, Darcy Graham, and Brean.
Alternatives: Ewan Ashman, Rory Sutherland, Will Heard, Johnny Gray, Marshall Sykes, Ben Munaxter, Jamie Dobby and Stafford McDowall.
1:33
Is this the best French team ever?
Tom Hamilton and James Regan discuss where this current French team is among the French rugby greats.
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